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Transcriptional control of Flt3 ligand targeted by fluorouracil-induced Egr-1 promoter in hematopoietic damage

BACKGROUND: Ionizing radiation (IR) activate the early growth response-1 (Egr-1) promoter by production of radical oxygen intermediates (ROIs). Egr-EF, an expression vector pCIneo containing Egr-1 promoter cloned upstream of the cDNA for Flt3 ligand, was used to treat hematopoietic damage. 5-fluorou...

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Detalles Bibliográficos
Autores principales:	Du, Nan, Pei, Xuetao, Zhou, Jinming, Zhao, Hui, Li, Xiaosong, Fu, Yan, Hao, Yixin
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761387/ https://www.ncbi.nlm.nih.gov/pubmed/19765320 http://dx.doi.org/10.1186/1423-0127-16-85

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