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Single Nucleotide Polymorphism Analysis of European Archaeological M. leprae DNA

BACKGROUND: Leprosy was common in Europe eight to twelve centuries ago but molecular confirmation of this has been lacking. We have extracted M. leprae ancient DNA (aDNA) from medieval bones and single nucleotide polymorphism (SNP) typed the DNA, this provides insight into the pattern of leprosy tra...

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Detalles Bibliográficos
Autores principales: Watson, Claire L., Lockwood, Diana N. J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761613/
https://www.ncbi.nlm.nih.gov/pubmed/19847306
http://dx.doi.org/10.1371/journal.pone.0007547