Cargando…

Alendronate Inhibits VEGF Expression in Growth Plate Chondrocytes by Acting on the Mevalonate Pathway

Bisphosphonates decrease chondrocyte turnover at the growth plate and impact bone growth. Likewise vascular endothelial growth factor (VEGF) plays an important role in endochondral bone elongation by influencing chondrocyte turnover at the growth plate. To investigate whether the action of bisphosph...

Descripción completa

Detalles Bibliográficos
Autores principales:	Evans, K.D, Oberbauer, A.M
Formato:	Texto
Lenguaje:	English
Publicado:	Bentham Open 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761671/ https://www.ncbi.nlm.nih.gov/pubmed/19834579 http://dx.doi.org/10.2174/1874325000903010083

Ejemplares similares

Alendronate, a double-edged sword acting in the mevalonate pathway
por: TRICARICO, PAOLA MAURA, et al.
Publicado: (2015)

Weekly oral alendronate in mevalonate kinase deficiency
por: Cantarini, Luca, et al.
Publicado: (2013)

Regulation of VEGF by mevalonate pathway inhibition in breast cancer
por: Rachner, Tilman D., et al.
Publicado: (2013)

Fibroblast growth factor receptor 3 effects on proliferation and telomerase activity in sheep growth plate chondrocytes
por: Smith, Logan B, et al.
Publicado: (2012)

Inhibition of the mevalonate pathway improves myocardial fibrosis
por: Xu, Huifeng, et al.
Publicado: (2021)

ASPP2 inhibits tumor growth by repressing the mevalonate pathway in hepatocellular carcinoma
por: Liang, Beibei, et al.
Publicado: (2019)

Expression of housekeeping genes varies depending on mevalonate pathway inhibition in cancer cells
por: Irie, Nanami, et al.
Publicado: (2023)

The mevalonate pathway in C. Elegans
por: Rauthan, Manish, et al.
Publicado: (2011)

Valproic Acid Impacts the Growth of Growth Plate Chondrocytes
por: Fan, Hueng-Chuen, et al.
Publicado: (2020)

Growth Plate Chondrocytes: Skeletal Development, Growth and Beyond
por: Hallett, Shawn A., et al.
Publicado: (2019)

Long Term Cyclic Pamidronate Reduces Bone Growth by Inhibiting Osteoclast Mediated Cartilage-to-Bone Turnover in the Mouse
por: Evans, K.D, et al.
Publicado: (2008)

Activation of the plant mevalonate pathway by extracellular ATP
por: Cho, Sung-Hwan, et al.
Publicado: (2022)

Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells
por: Karlic, Heidrun, et al.
Publicado: (2015)

Anti-tumor effects of mevalonate pathway inhibition in ovarian cancer
por: Göbel, Andy, et al.
Publicado: (2020)

Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence
por: Wei, Shupei, et al.
Publicado: (2019)

Nicotine Acts on Growth Plate Chondrocytes to Delay Skeletal Growth through the α7 Neuronal Nicotinic Acetylcholine Receptor
por: Kawakita, Atsuo, et al.
Publicado: (2008)

Genomic variations of the mevalonate pathway in porokeratosis
por: Zhang, Zhenghua, et al.
Publicado: (2015)

The Mevalonate Pathway Is Indispensable for Adipocyte Survival
por: Yeh, Yu-Sheng, et al.
Publicado: (2018)

The Mevalonate Pathway Is Important for Growth, Spore Production, and the Virulence of Phytophthora sojae
por: Yang, Xinyu, et al.
Publicado: (2021)

Regulation of Gene Expression by PI3K in Mouse Growth Plate Chondrocytes
por: Ulici, Veronica, et al.
Publicado: (2010)

MicroRNA-874 targets phosphomevalonate kinase and inhibits cancer cell growth via the mevalonate pathway
por: Aersilan, Alimasi, et al.
Publicado: (2022)

Cyclooxygenases and prostaglandin E(2 )receptors in growth plate chondrocytes in vitro and in situ – prostaglandin E(2 )dependent proliferation of growth plate chondrocytes
por: Brochhausen, Christoph, et al.
Publicado: (2006)

Delphinidin Inhibits Tumor Growth by Acting on VEGF Signalling in Endothelial Cells
por: Keravis, Thérèse, et al.
Publicado: (2015)

Synthesis of Heterologous Mevalonic Acid Pathway Enzymes in Clostridium ljungdahlii for the Conversion of Fructose and of Syngas to Mevalonate and Isoprene
por: Diner, Bruce A., et al.
Publicado: (2017)

Inhibition of the mevalonate pathway augments the activity of pitavastatin against ovarian cancer cells
por: Abdullah, Marwan Ibrahim, et al.
Publicado: (2017)

Inhibition of Orbivirus Replication by Fluvastatin and Identification of the Key Elements of the Mevalonate Pathway Involved
por: Mohd Jaafar, Fauziah, et al.
Publicado: (2021)

Bisphosphonate drugs have actions in the lung and inhibit the mevalonate pathway in alveolar macrophages
por: Munoz, Marcia A, et al.
Publicado: (2021)

Evidence of a Novel Mevalonate Pathway in Archaea
por: Vinokur, Jeffrey M., et al.
Publicado: (2014)

Correction: Genomic variations of the mevalonate pathway in porokeratosis
por: Zhang, Zhenghua, et al.
Publicado: (2016)

Control of the innate immune response by the mevalonate pathway
por: Akula, Murali K., et al.
Publicado: (2016)

Carboxypeptidase Z (CPZ) Links Thyroid Hormone and Wnt Signaling Pathways in Growth Plate Chondrocytes
por: Wang, Lai, et al.
Publicado: (2009)

Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte
por: Klooster, Aaron R, et al.
Publicado: (2005)

Crystal structure of mevalonate 3,5-bisphosphate decarboxylase reveals insight into the evolution of decarboxylases in the mevalonate metabolic pathways
por: Aoki, Mizuki, et al.
Publicado: (2022)

Pamidronate Alters the Growth Plate in the Oim Mouse Model for Osteogenesis Imperfecta
por: Evans, K. D., et al.
Publicado: (2009)

NRF3 upregulates gene expression in SREBP2-dependent mevalonate pathway with cholesterol uptake and lipogenesis inhibition
por: Waku, Tsuyoshi, et al.
Publicado: (2021)

Mevalonate kinase deficiencies: from mevalonic aciduria to hyperimmunoglobulinemia D syndrome
por: Haas, Dorothea, et al.
Publicado: (2006)

Importance of Mevalonate Pathway Lipids on the Growth and Survival of Primary and Metastatic Gastric Carcinoma Cells
por: Ortiz, Natalia, et al.
Publicado: (2021)

Changes in Gene Expression Associated with Matrix Turnover, Chondrocyte Proliferation and Hypertrophy in the Bovine Growth Plate
por: Tchetina, E. V., et al.
Publicado: (2014)

PPARγ2 expression in growth plate chondrocytes is regulated by p38 and GSK-3
por: Stanton, Lee-Anne, et al.
Publicado: (2010)

Genes uniquely expressed in human growth plate chondrocytes uncover a distinct regulatory network
por: Li, Bing, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_3bdj5m4i32squ66hkhpudu5lfr