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Regulatory activity of azabisphosphonate-capped dendrimers on human CD4(+ )T cell proliferation enhances ex-vivo expansion of NK cells from PBMCs for immunotherapy
BACKGROUND: Adoptive cell therapy with allogenic NK cells constitutes a promising approach for the treatment of certain malignancies. Such strategies are currently limited by the requirement of an efficient protocol for NK cell expansion. We have developed a method using synthetic nanosized phosphon...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761872/ https://www.ncbi.nlm.nih.gov/pubmed/19778420 http://dx.doi.org/10.1186/1479-5876-7-82 |