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Towards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation
BACKGROUND: The cell cycle is a complex process that allows eukaryotic cells to replicate chromosomal DNA and partition it into two daughter cells. A relevant regulatory step is in the G(0)/G(1 )phase, a point called the restriction (R) point where intracellular and extracellular signals are monitor...
Autores principales: | Alfieri, Roberta, Barberis, Matteo, Chiaradonna, Ferdinando, Gaglio, Daniela, Milanesi, Luciano, Vanoni, Marco, Klipp, Edda, Alberghina, Lilia |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762065/ https://www.ncbi.nlm.nih.gov/pubmed/19828076 http://dx.doi.org/10.1186/1471-2105-10-S12-S16 |
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