Cargando…

Molecular modeling of swine influenza A/H1N1, Spanish H1N1, and avian H5N1 flu N1 neuraminidases bound to Tamiflu and Relenza

A molecular model of the swine influenza A/H1N1 ( also called H1N1pdm) type-I neuraminidase was built using the pathogenic avian H5N1 type-I neuraminidase as a basis, due to the higher sequence identity between A/H1N1 and H5N1 (91.47%) compared to Spanish H1N1 (88.37%) neuraminidase. All-atom molecu...

Descripción completa

Detalles Bibliográficos
Autores principales: Le, Ly, Lee, Eric, Schulten, Klaus, Truong, Thanh N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762416/
https://www.ncbi.nlm.nih.gov/pubmed/20029609
http://dx.doi.org/10.1371/currents.RRN1015