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Enhanced Edar Signalling Has Pleiotropic Effects on Craniofacial and Cutaneous Glands

The skin carries a number of appendages, including hair follicles and a range of glands, which develop under the influence of EDAR signalling. A gain of function allele of EDAR is found at high frequency in human populations of East Asia, with genetic evidence suggesting recent positive selection at...

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Detalles Bibliográficos
Autores principales: Chang, Shie Hong, Jobling, Stephanie, Brennan, Keith, Headon, Denis J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762540/
https://www.ncbi.nlm.nih.gov/pubmed/19855838
http://dx.doi.org/10.1371/journal.pone.0007591