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Collection of Macaca fascicularis cDNAs derived from bone marrow, kidney, liver, pancreas, spleen, and thymus

BACKGROUND: Consolidating transcriptome data of non-human primates is essential to annotate primate genome sequences, and will facilitate research using non-human primates in the genomic era. Macaca fascicularis is a macaque monkey that is commonly used for biomedical and ecological research. FINDIN...

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Detalles Bibliográficos
Autores principales: Osada, Naoki, Hirata, Makoto, Tanuma, Reiko, Suzuki, Yutaka, Sugano, Sumio, Terao, Keiji, Kusuda, Jun, Kameoka, Yosuke, Hashimoto, Katsuyuki, Takahashi, Ichiro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762985/
https://www.ncbi.nlm.nih.gov/pubmed/19785770
http://dx.doi.org/10.1186/1756-0500-2-199
Descripción
Sumario:BACKGROUND: Consolidating transcriptome data of non-human primates is essential to annotate primate genome sequences, and will facilitate research using non-human primates in the genomic era. Macaca fascicularis is a macaque monkey that is commonly used for biomedical and ecological research. FINDINGS: We constructed cDNA libraries of Macaca fascicularis, derived from tissues obtained from bone marrow, liver, pancreas, spleen, and thymus of a young male, and kidney of a young female. In total, 5'-end sequences of 56,856 clones were determined. Including the previously established cDNA libraries from brain and testis, we have isolated 112,587 cDNAs of Macaca fascicularis, which correspond to 56% of the curated human reference genes. CONCLUSION: These sequences were deposited in the public sequence database as well as in-house macaque genome database . These data will become valuable resources for identifying functional parts of the genome of macaque monkeys in future studies.