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[(11)C]-DPA-713 and [(18)F]-DPA-714 as New PET Tracers for TSPO: A Comparison with [(11)C]-(R)-PK11195 in a Rat Model of Herpes Encephalitis

BACKGROUND: Activation of microglia cells plays an important role in neurological diseases. Positron emission tomography (PET) with [(11)C]-(R)-PK11195 has already been used to visualize activated microglia cells in neurological diseases. However, [(11)C]-(R)-PK11195 may not possess the required sen...

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Detalles Bibliográficos
Autores principales:	Doorduin, Janine, Klein, Hans C., Dierckx, Rudi A., James, Michelle, Kassiou, Michael, de Vries, Erik F. J.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763079/ https://www.ncbi.nlm.nih.gov/pubmed/19330384 http://dx.doi.org/10.1007/s11307-009-0211-6

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