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1,5-Diazacyclohenicosane, a New Cytotoxic Metabolite from the Marine Sponge Mycale sp
A new cyclic diamine, 1,5-diazacyclohenicosane (1), was isolated from samples of the marine sponge Mycale sp. collected at Lamu Island (Kenya). Its structure was determined by a combination of spectroscopic techniques, including (+)-HRESIMS and 1D and 2D NMR spectroscopy. The compound displayed cyto...
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Formato: | Texto |
Lenguaje: | English |
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Molecular Diversity Preservation International
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763110/ https://www.ncbi.nlm.nih.gov/pubmed/19841724 http://dx.doi.org/10.3390/md7030445 |
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author | Coello, Laura Martín, María Jesús Reyes, Fernando |
author_facet | Coello, Laura Martín, María Jesús Reyes, Fernando |
author_sort | Coello, Laura |
collection | PubMed |
description | A new cyclic diamine, 1,5-diazacyclohenicosane (1), was isolated from samples of the marine sponge Mycale sp. collected at Lamu Island (Kenya). Its structure was determined by a combination of spectroscopic techniques, including (+)-HRESIMS and 1D and 2D NMR spectroscopy. The compound displayed cytotoxicity at the μM level against three human tumor cell lines. |
format | Text |
id | pubmed-2763110 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Molecular Diversity Preservation International |
record_format | MEDLINE/PubMed |
spelling | pubmed-27631102009-10-19 1,5-Diazacyclohenicosane, a New Cytotoxic Metabolite from the Marine Sponge Mycale sp Coello, Laura Martín, María Jesús Reyes, Fernando Mar Drugs Article A new cyclic diamine, 1,5-diazacyclohenicosane (1), was isolated from samples of the marine sponge Mycale sp. collected at Lamu Island (Kenya). Its structure was determined by a combination of spectroscopic techniques, including (+)-HRESIMS and 1D and 2D NMR spectroscopy. The compound displayed cytotoxicity at the μM level against three human tumor cell lines. Molecular Diversity Preservation International 2009-09-15 /pmc/articles/PMC2763110/ /pubmed/19841724 http://dx.doi.org/10.3390/md7030445 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Coello, Laura Martín, María Jesús Reyes, Fernando 1,5-Diazacyclohenicosane, a New Cytotoxic Metabolite from the Marine Sponge Mycale sp |
title | 1,5-Diazacyclohenicosane, a New Cytotoxic Metabolite from the Marine Sponge Mycale sp |
title_full | 1,5-Diazacyclohenicosane, a New Cytotoxic Metabolite from the Marine Sponge Mycale sp |
title_fullStr | 1,5-Diazacyclohenicosane, a New Cytotoxic Metabolite from the Marine Sponge Mycale sp |
title_full_unstemmed | 1,5-Diazacyclohenicosane, a New Cytotoxic Metabolite from the Marine Sponge Mycale sp |
title_short | 1,5-Diazacyclohenicosane, a New Cytotoxic Metabolite from the Marine Sponge Mycale sp |
title_sort | 1,5-diazacyclohenicosane, a new cytotoxic metabolite from the marine sponge mycale sp |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763110/ https://www.ncbi.nlm.nih.gov/pubmed/19841724 http://dx.doi.org/10.3390/md7030445 |
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