Excavatoids E and F: Discovery of Two New Briaranes from the Cultured Octocoral Briareum excavatum

Two new briarane-related diterpenoids, designated as excavatoids E (1) and F (2), were isolated from the cultured octocoral Briareum excavatum. The structures of compounds 1 and 2 were established on the basis of extensive spectral data analysis. Briaranes 1 and 2 were found to exhibit moderate inhi...

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Detalles Bibliográficos
Autores principales: Sung, Ping-Jyun, Chen, Bo-Yuan, Lin, Mei-Ru, Hwang, Tsong-Long, Wang, Wei-Hsien, Sheu, Jyh-Horng, Wu, Yang-Chang
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763113/
https://www.ncbi.nlm.nih.gov/pubmed/19841727
http://dx.doi.org/10.3390/md7030472
Descripción
Sumario:Two new briarane-related diterpenoids, designated as excavatoids E (1) and F (2), were isolated from the cultured octocoral Briareum excavatum. The structures of compounds 1 and 2 were established on the basis of extensive spectral data analysis. Briaranes 1 and 2 were found to exhibit moderate inhibitory effects on elastase release by human neutrophils.

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