Excavatoids E and F: Discovery of Two New Briaranes from the Cultured Octocoral Briareum excavatum

Two new briarane-related diterpenoids, designated as excavatoids E (1) and F (2), were isolated from the cultured octocoral Briareum excavatum. The structures of compounds 1 and 2 were established on the basis of extensive spectral data analysis. Briaranes 1 and 2 were found to exhibit moderate inhi...

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Autores principales: Sung, Ping-Jyun, Chen, Bo-Yuan, Lin, Mei-Ru, Hwang, Tsong-Long, Wang, Wei-Hsien, Sheu, Jyh-Horng, Wu, Yang-Chang
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763113/
https://www.ncbi.nlm.nih.gov/pubmed/19841727
http://dx.doi.org/10.3390/md7030472
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author Sung, Ping-Jyun
Chen, Bo-Yuan
Lin, Mei-Ru
Hwang, Tsong-Long
Wang, Wei-Hsien
Sheu, Jyh-Horng
Wu, Yang-Chang
author_facet Sung, Ping-Jyun
Chen, Bo-Yuan
Lin, Mei-Ru
Hwang, Tsong-Long
Wang, Wei-Hsien
Sheu, Jyh-Horng
Wu, Yang-Chang
author_sort Sung, Ping-Jyun
collection PubMed
description Two new briarane-related diterpenoids, designated as excavatoids E (1) and F (2), were isolated from the cultured octocoral Briareum excavatum. The structures of compounds 1 and 2 were established on the basis of extensive spectral data analysis. Briaranes 1 and 2 were found to exhibit moderate inhibitory effects on elastase release by human neutrophils.
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spelling pubmed-27631132009-10-19 Excavatoids E and F: Discovery of Two New Briaranes from the Cultured Octocoral Briareum excavatum Sung, Ping-Jyun Chen, Bo-Yuan Lin, Mei-Ru Hwang, Tsong-Long Wang, Wei-Hsien Sheu, Jyh-Horng Wu, Yang-Chang Mar Drugs Article Two new briarane-related diterpenoids, designated as excavatoids E (1) and F (2), were isolated from the cultured octocoral Briareum excavatum. The structures of compounds 1 and 2 were established on the basis of extensive spectral data analysis. Briaranes 1 and 2 were found to exhibit moderate inhibitory effects on elastase release by human neutrophils. Molecular Diversity Preservation International 2009-09-23 /pmc/articles/PMC2763113/ /pubmed/19841727 http://dx.doi.org/10.3390/md7030472 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Sung, Ping-Jyun
Chen, Bo-Yuan
Lin, Mei-Ru
Hwang, Tsong-Long
Wang, Wei-Hsien
Sheu, Jyh-Horng
Wu, Yang-Chang
Excavatoids E and F: Discovery of Two New Briaranes from the Cultured Octocoral Briareum excavatum
title Excavatoids E and F: Discovery of Two New Briaranes from the Cultured Octocoral Briareum excavatum
title_full Excavatoids E and F: Discovery of Two New Briaranes from the Cultured Octocoral Briareum excavatum
title_fullStr Excavatoids E and F: Discovery of Two New Briaranes from the Cultured Octocoral Briareum excavatum
title_full_unstemmed Excavatoids E and F: Discovery of Two New Briaranes from the Cultured Octocoral Briareum excavatum
title_short Excavatoids E and F: Discovery of Two New Briaranes from the Cultured Octocoral Briareum excavatum
title_sort excavatoids e and f: discovery of two new briaranes from the cultured octocoral briareum excavatum
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763113/
https://www.ncbi.nlm.nih.gov/pubmed/19841727
http://dx.doi.org/10.3390/md7030472
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