Metallothionein induction reduces caspase-3 activity and TNFα levels with preservation of cognitive function and intact hippocampal neurons in carmustine-treated rats

Hippocampal integrity is essential for cognitive functions. On the other hand, induction of metallothionein (MT) by ZnSO(4) and its role in neuroprotection has been documented. The present study aimed to explore the effect of MT induction on carmustine (BCNU)-induced hippocampal cognitive dysfunctio...

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Detalles Bibliográficos
Autores principales: Helal, Gouda K, Aleisa, Abdulaziz M, Helal, Omayma K, Al-Rejaie, Salim S, Al-Yahya, Abdulaziz A, Al-Majed, Abdulhakeem A, Al-Shabanah, Othman A
Formato: Texto
Lenguaje:English
Publicado: Landes Bioscience 2009
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763228/
https://www.ncbi.nlm.nih.gov/pubmed/20046642

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