Cargando…
Usa1 Protein Facilitates Substrate Ubiquitylation through Two Separate Domains
BACKGROUND: Defects in protein folding are recognized as the root of many neurodegenerative disorders. In the endoplasmic reticulum (ER), secretory proteins are subjected to a stringent quality control process to eliminate misfolded proteins by the ER-associated degradation (ERAD) pathway. A novel E...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764048/ https://www.ncbi.nlm.nih.gov/pubmed/19898607 http://dx.doi.org/10.1371/journal.pone.0007604 |