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Detection of amyloid in Alzheimer’s disease with positron emission tomography using [(11)C]AZD2184

PURPOSE: Current positron emission tomography (PET) radioligands for detection of Aβ amyloid in Alzheimer’s disease (AD) are not ideal for quantification. To improve the signal to noise ratio we have developed the radioligand [(11)C]AZD2184 and report here the first clinical evaluation. METHODS: Eig...

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Detalles Bibliográficos
Autores principales: Nyberg, Svante, Jönhagen, Maria Eriksdotter, Cselényi, Zsolt, Halldin, Christer, Julin, Per, Olsson, Hans, Freund-Levi, Yvonne, Andersson, Jan, Varnäs, Katarina, Svensson, Samuel, Farde, Lars
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764092/
https://www.ncbi.nlm.nih.gov/pubmed/19495746
http://dx.doi.org/10.1007/s00259-009-1182-1