A multi PDZ-domain protein Pdzd2 contributes to functional expression of sensory neuron-specific sodium channel Na(V)1.8

The voltage-gated sodium channel Na(V)1.8 is expressed exclusively in nociceptive sensory neurons and plays an important role in pain pathways. Na(V)1.8 cannot be functionally expressed in non-neuronal cells even in the presence of β-subunits. We have previously identified Pdzd2, a multi PDZ-domain...

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Detalles Bibliográficos
Autores principales: Shao, Dongmin, Baker, Mark D., Abrahamsen, Bjarke, Rugiero, Francois, Malik-Hall, Misbah, Poon, W.-Y. Louisa, Cheah, Kathryn S.E., Yao, Kwok-Ming, Wood, John N., Okuse, Kenji
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764382/
https://www.ncbi.nlm.nih.gov/pubmed/19607921
http://dx.doi.org/10.1016/j.mcn.2009.07.003

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