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Improvement of RNA secondary structure prediction using RNase H cleavage and randomized oligonucleotides
RNA secondary structure prediction using free energy minimization is one method to gain an approximation of structure. Constraints generated by enzymatic mapping or chemical modification can improve the accuracy of secondary structure prediction. We report a facile method that identifies single-stra...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764423/ https://www.ncbi.nlm.nih.gov/pubmed/19596816 http://dx.doi.org/10.1093/nar/gkp587 |