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Differential contribution of the m(7)G-cap to the 5′ end-dependent translation initiation of mammalian mRNAs
Many mammalian mRNAs possess long 5′ UTRs with numerous stem-loop structures. For some of them, the presence of Internal Ribosome Entry Sites (IRESes) was suggested to explain their significant activity, especially when cap-dependent translation is compromised. To test this hypothesis, we have compa...
Autores principales: | Andreev, Dmitri E., Dmitriev, Sergey E., Terenin, Ilya M., Prassolov, Vladimir S., Merrick, William C., Shatsky, Ivan N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764426/ https://www.ncbi.nlm.nih.gov/pubmed/19696074 http://dx.doi.org/10.1093/nar/gkp665 |
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