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Open chromatin encoded in DNA sequence is the signature of ‘master’ replication origins in human cells
For years, progress in elucidating the mechanisms underlying replication initiation and its coupling to transcriptional activities and to local chromatin structure has been hampered by the small number (approximately 30) of well-established origins in the human genome and more generally in mammalian...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764438/ https://www.ncbi.nlm.nih.gov/pubmed/19671527 http://dx.doi.org/10.1093/nar/gkp631 |