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The human telomerase RNA component, hTR, activates the DNA-dependent protein kinase to phosphorylate heterogeneous nuclear ribonucleoprotein A1

Telomere integrity in human cells is maintained by the dynamic interplay between telomerase, telomere associated proteins, and DNA repair proteins. These interactions are vital to suppress DNA damage responses and unfavorable changes in chromosome dynamics. The DNA-dependent protein kinase (DNA-PK)...

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Detalles Bibliográficos
Autores principales: Ting, Nicholas S. Y., Pohorelic, Brant, Yu, Yaping, Lees-Miller, Susan P., Beattie, Tara L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764450/
https://www.ncbi.nlm.nih.gov/pubmed/19656952
http://dx.doi.org/10.1093/nar/gkp636

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