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Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling
BACKGROUND: The understanding of regulatory and signaling networks has long been a core objective in Systems Biology. Knowledge about these networks is mainly of qualitative nature, which allows the construction of Boolean models, where the state of a component is either 'off' or 'on&...
Autores principales: | Wittmann, Dominik M, Krumsiek, Jan, Saez-Rodriguez, Julio, Lauffenburger, Douglas A, Klamt, Steffen, Theis, Fabian J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764636/ https://www.ncbi.nlm.nih.gov/pubmed/19785753 http://dx.doi.org/10.1186/1752-0509-3-98 |
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