Role of CA125 in predicting ovarian cancer survival - a review of the epidemiological literature

CA125 is the gold standard tumor marker in ovarian cancer. Serum level of CA125 is used to monitor response to chemotherapy, relapse, and disease progression in ovarian cancer patients. Thus, it is reasonable to investigate whether CA125 may have utility as a prognostic indicator as well in ovarian...

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Detalles Bibliográficos
Autores principales: Gupta, Digant, Lis, Christopher G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764643/
https://www.ncbi.nlm.nih.gov/pubmed/19818123
http://dx.doi.org/10.1186/1757-2215-2-13
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author Gupta, Digant
Lis, Christopher G
author_facet Gupta, Digant
Lis, Christopher G
author_sort Gupta, Digant
collection PubMed
description CA125 is the gold standard tumor marker in ovarian cancer. Serum level of CA125 is used to monitor response to chemotherapy, relapse, and disease progression in ovarian cancer patients. Thus, it is reasonable to investigate whether CA125 may have utility as a prognostic indicator as well in ovarian cancer. A large number of epidemiological studies have been carried out to this effect. This review summarizes all available epidemiological literature on the association between CA125 levels and survival in ovarian cancer. To place these studies in context, we provide some background information on CA125 and its role in ovarian cancer.
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spelling pubmed-27646432009-10-21 Role of CA125 in predicting ovarian cancer survival - a review of the epidemiological literature Gupta, Digant Lis, Christopher G J Ovarian Res Review CA125 is the gold standard tumor marker in ovarian cancer. Serum level of CA125 is used to monitor response to chemotherapy, relapse, and disease progression in ovarian cancer patients. Thus, it is reasonable to investigate whether CA125 may have utility as a prognostic indicator as well in ovarian cancer. A large number of epidemiological studies have been carried out to this effect. This review summarizes all available epidemiological literature on the association between CA125 levels and survival in ovarian cancer. To place these studies in context, we provide some background information on CA125 and its role in ovarian cancer. BioMed Central 2009-10-09 /pmc/articles/PMC2764643/ /pubmed/19818123 http://dx.doi.org/10.1186/1757-2215-2-13 Text en Copyright © 2009 Gupta and Lis; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Gupta, Digant
Lis, Christopher G
Role of CA125 in predicting ovarian cancer survival - a review of the epidemiological literature
title Role of CA125 in predicting ovarian cancer survival - a review of the epidemiological literature
title_full Role of CA125 in predicting ovarian cancer survival - a review of the epidemiological literature
title_fullStr Role of CA125 in predicting ovarian cancer survival - a review of the epidemiological literature
title_full_unstemmed Role of CA125 in predicting ovarian cancer survival - a review of the epidemiological literature
title_short Role of CA125 in predicting ovarian cancer survival - a review of the epidemiological literature
title_sort role of ca125 in predicting ovarian cancer survival - a review of the epidemiological literature
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764643/
https://www.ncbi.nlm.nih.gov/pubmed/19818123
http://dx.doi.org/10.1186/1757-2215-2-13
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