Cargando…
Stable replication of the EBNA1/OriP-mediated baculovirus vector and its application to anti-HCV gene therapy
BACKGROUND: Hepatitis C virus (HCV) is one of the main causes of liver-related morbidity and mortality. Although combined interferon-α-ribavirin therapy is effective for about 50% of the patients with HCV, better therapies are needed and preventative vaccines have yet to be developed. Short-hairpin...
Autores principales: | Suzuki, Hitoshi, Matsumoto, Norihiko, Suzuki, Tomoyuki, Chang, Myint OO, Takaku, Hiroshi |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764697/ https://www.ncbi.nlm.nih.gov/pubmed/19796392 http://dx.doi.org/10.1186/1743-422X-6-156 |
Ejemplares similares
-
Long-term transgene expression and inhibition of HIV-1 replication by a Cre/loxP-EBNA-1/oriP HIV-1-dependent ribozyme vector: Applications for HIV-1 gene therapy
por: Nagawa, Takashi, et al.
Publicado: (2006) -
Regulated expression of a transgene introduced on an oriP/EBNA-1 PAC shuttle vector into human cells
por: Askautrud, Hanne A, et al.
Publicado: (2009) -
Retrofitting BACs with G418 resistance, luciferase, and oriP and EBNA-1 – new vectors for in vitro and in vivo delivery
por: Magin-Lachmann, Christine, et al.
Publicado: (2003) -
Generation of human iPSCs from cells of fibroblastic and epithelial origin by means of the oriP/EBNA-1 episomal reprogramming system
por: Drozd, Anna M., et al.
Publicado: (2015) -
HCF1 and OCT2 Cooperate with EBNA1 To Enhance OriP-Dependent Transcription and Episome Maintenance of Latent Epstein-Barr Virus
por: Dheekollu, Jayaraju, et al.
Publicado: (2016)