Cargando…

An endogenous peptide positively selects and augments peripheral CD4(+) T cell activation and survival

Although CD4(+) and CD8(+) T cells differ in their positively selecting signal strength, endogenous positively selecting ligands have only been identified for MHC class I-restricted T cell receptors (TCRs). Here we screened for ligands that can positively select MHC class II-restricted TCRs, using t...

Descripción completa

Detalles Bibliográficos
Autores principales: Lo, Wan-Lin, Felix, Nathan J., Walters, James J., Rohrs, Henry, Gross, Michael L., Allen, Paul M.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764840/
https://www.ncbi.nlm.nih.gov/pubmed/19801984
http://dx.doi.org/10.1038/ni.1796