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An endogenous peptide positively selects and augments peripheral CD4(+) T cell activation and survival
Although CD4(+) and CD8(+) T cells differ in their positively selecting signal strength, endogenous positively selecting ligands have only been identified for MHC class I-restricted T cell receptors (TCRs). Here we screened for ligands that can positively select MHC class II-restricted TCRs, using t...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764840/ https://www.ncbi.nlm.nih.gov/pubmed/19801984 http://dx.doi.org/10.1038/ni.1796 |