Reciprocal t(9;22) ABL/BCR Fusion Proteins: Leukemogenic Potential and Effects on B Cell Commitment

BACKGROUND: t(9;22) is a balanced translocation, and the chromosome 22 breakpoints (Philadelphia chromosome – Ph(+)) determine formation of different fusion genes that are associated with either Ph(+) acute lymphatic leukemia (Ph(+) ALL) or chronic myeloid leukemia (CML). The “minor” breakpoint in P...

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Detalles Bibliográficos
Autores principales: Zheng, Xiaomin, Oancea, Claudia, Henschler, Reinhard, Moore, Malcolm A. S., Ruthardt, Martin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764858/
https://www.ncbi.nlm.nih.gov/pubmed/19876398
http://dx.doi.org/10.1371/journal.pone.0007661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764858/
https://www.ncbi.nlm.nih.gov/pubmed/19876398
http://dx.doi.org/10.1371/journal.pone.0007661

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