dSir2 and Dmp53 interact to mediate aspects of CR-dependent life span extension in D. melanogaster

Calorie Restriction (CR) is a well established method of extending life span in a variety of organisms. In the fruit fly D. melanogaster, CR is mediated at least in part by activation of dSir2. In mammalian systems, one of the critical targets of Sir2 is the tumor suppressor p53. This deacetylation...

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Detalles Bibliográficos
Autores principales: Bauer, Johannes H., Morris, Siti Nur Sarah, Chang, Chengyi, Flatt*, Thomas, Wood, Jason G., Helfand, Stephen L.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765060/
https://www.ncbi.nlm.nih.gov/pubmed/19851477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765060/
https://www.ncbi.nlm.nih.gov/pubmed/19851477

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