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Hepatitis B virus inhibition in mice by lentiviral vector mediated short hairpin RNA
BACKGROUND: Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma. The major challenges for current therapies are the low efficacy of current drugs and the occurrence of drug resistant HBV mutations. RNA interference (RNAi) of virus-specific genes...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765442/ https://www.ncbi.nlm.nih.gov/pubmed/19804649 http://dx.doi.org/10.1186/1471-230X-9-73 |