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Hepatitis B virus inhibition in mice by lentiviral vector mediated short hairpin RNA

BACKGROUND: Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma. The major challenges for current therapies are the low efficacy of current drugs and the occurrence of drug resistant HBV mutations. RNA interference (RNAi) of virus-specific genes...

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Detalles Bibliográficos
Autores principales:	Deng, Lei, Li, Guoqiang, Xi, Lisen, Yin, Aihong, Gao, Yun, You, Wei, Wang, Xuehao, Sun, Beicheng
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765442/ https://www.ncbi.nlm.nih.gov/pubmed/19804649 http://dx.doi.org/10.1186/1471-230X-9-73

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