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Prior treatment with vitamin K(2) significantly improves the efficacy of risedronate

SUMMARY: Prior 8-week treatment with menatetrenone, MK-4, followed by 8-week risedronate prevented the shortcomings of individual drugs and significantly increased the strength of ovariectomized ICR mouse femur compared to the ovariectomized (OVX) controls. Neither MK-4 following risedronate nor the...

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Detalles Bibliográficos
Autores principales: Matsumoto, Y., Mikuni-Takagaki, Y., Kozai, Y., Miyagawa, K., Naruse, K., Wakao, H., Kawamata, R., Kashima, I., Sakurai, T.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765650/
https://www.ncbi.nlm.nih.gov/pubmed/19280272
http://dx.doi.org/10.1007/s00198-009-0888-z