A novel inhibitor of Chlamydophila pneumoniae protein kinase D (PknD) inhibits phosphorylation of CdsD and suppresses bacterial replication

BACKGROUND: We have shown previously that Chlamydophila pneumoniae contains a dual-specific Ser/Thr protein kinase that phosphorylates CdsD, a structural component of the type III secretion apparatus. To further study the role of PknD in growth and development we sought to identify a PknD inhibitor...

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Detalles Bibliográficos
Autores principales: Johnson, Dustin L, Stone, Chris B, Bulir, David C, Coombes, Brian K, Mahony, James B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765968/
https://www.ncbi.nlm.nih.gov/pubmed/19828035
http://dx.doi.org/10.1186/1471-2180-9-218

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