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Fyn Mediates Leptin Actions in the Thymus of Rodents

BACKGROUND: Several effects of leptin in the immune system rely on its capacity to modulate cytokine expression and apoptosis in the thymus. Surprisingly, some of these effects are dependent on signal transduction through the IRS1/PI3-kinase, but not on the activation of JAK2. Since all the well kno...

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Detalles Bibliográficos
Autores principales: Girasol, Alessandra, Albuquerque, Gabriela G., Mansour, Eli, Araújo, Eliana P., Degasperi, Giovanna, Denis, Raphael G., Carvalheira, José B., Saad, Mário J., Velloso, Lício A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766049/
https://www.ncbi.nlm.nih.gov/pubmed/19888448
http://dx.doi.org/10.1371/journal.pone.0007707

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