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The E3 Ubiquitin Ligase Triad3A Negatively Regulates the RIG-I/MAVS Signaling Pathway by Targeting TRAF3 for Degradation

The primary role of the innate immune response is to limit the spread of infectious pathogens, with activation of Toll-like receptor (TLR) and RIG-like receptor (RLR) pathways resulting in a pro-inflammatory response required to combat infection. Limiting the activation of these signaling pathways i...

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Detalles Bibliográficos
Autores principales:	Nakhaei, Peyman, Mesplede, Thibault, Solis, Mayra, Sun, Qiang, Zhao, Tiejun, Yang, Long, Chuang, Tsung-Hsien, Ware, Carl F., Lin, Rongtuan, Hiscott, John
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766052/ https://www.ncbi.nlm.nih.gov/pubmed/19893624 http://dx.doi.org/10.1371/journal.ppat.1000650

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