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Evolution of Resistance to Targeted Anti-Cancer Therapies during Continuous and Pulsed Administration Strategies

The discovery of small molecules targeted to specific oncogenic pathways has revolutionized anti-cancer therapy. However, such therapy often fails due to the evolution of acquired resistance. One long-standing question in clinical cancer research is the identification of optimum therapeutic administ...

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Detalles Bibliográficos
Autores principales: Foo, Jasmine, Michor, Franziska
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766072/
https://www.ncbi.nlm.nih.gov/pubmed/19893626
http://dx.doi.org/10.1371/journal.pcbi.1000557

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