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miR-124 regulates adult neurogenesis in the SVZ stem cell niche
The subventricular zone (SVZ) is the largest neurogenic niche in the adult mammalian brain. Here we show that the brain-enriched microRNA miR-124 is an important regulator of the temporal progression of adult neurogenesis in mice. Knockdown of endogenous miR-124 maintains purified SVZ stem cells as...
Autores principales: | Cheng, Li-Chun, Pastrana, Erika, Tavazoie, Masoud, Doetsch, Fiona |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766245/ https://www.ncbi.nlm.nih.gov/pubmed/19287386 http://dx.doi.org/10.1038/nn.2294 |
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