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BRCA1/2 genetic background-based therapeutic tailoring of human ovarian cancer: hope or reality?
Ovarian epithelial tumors are an hallmark of hereditary cancer syndromes which are related to the germ-line inheritance of cancer predisposing mutations in BRCA1 and BRCA2 genes. Although these genes have been associated with multiple different physiologic functions, they share an important role in...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766378/ https://www.ncbi.nlm.nih.gov/pubmed/19825178 http://dx.doi.org/10.1186/1757-2215-2-14 |