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BRCA1/2 genetic background-based therapeutic tailoring of human ovarian cancer: hope or reality?

Ovarian epithelial tumors are an hallmark of hereditary cancer syndromes which are related to the germ-line inheritance of cancer predisposing mutations in BRCA1 and BRCA2 genes. Although these genes have been associated with multiple different physiologic functions, they share an important role in...

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Detalles Bibliográficos
Autores principales: Tagliaferri, Pierosandro, Ventura, Monica, Baudi, Francesco, Cucinotto, Iole, Arbitrio, Mariamena, Di Martino, Maria Teresa, Tassone, Pierfrancesco
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766378/
https://www.ncbi.nlm.nih.gov/pubmed/19825178
http://dx.doi.org/10.1186/1757-2215-2-14