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A Significant Increase of RNAi Efficiency in Human Cells by the CMV Enhancer with a tRNAlys Promoter

RNA interference (RNAi) is the process of mRNA degradation induced by double-stranded RNA in a sequence-specific manner. Different types of promoters, such as U6, H1, tRNA, and CMV, have been used to control the inhibitory effect of RNAi expression vectors. In the present study, we constructed two s...

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Detalles Bibliográficos
Autores principales: Weiwei, Ma, Zhenhua, Xie, Feng, Liu, Hang, Ning, Yuyang, Jiang
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766573/
https://www.ncbi.nlm.nih.gov/pubmed/19859553
http://dx.doi.org/10.1155/2009/514287