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IgG Antibodies against Measles, Rubella, and Varicella Zoster Virus Predict Conversion to Multiple Sclerosis in Clinically Isolated Syndrome

BACKGROUND: Multiple sclerosis (MS) is characterized by a polyspecific B-cell response to neurotropic viruses such as measles, rubella and varicella zoster, with the corresponding antibodies measurable in CSF as the so-called “MRZ reaction” (MRZR). We aimed to evaluate the relevance of MRZR to predi...

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Detalles Bibliográficos
Autores principales:	Brettschneider, Johannes, Tumani, Hayrettin, Kiechle, Ulrike, Muche, Rainer, Richards, Gayle, Lehmensiek, Vera, Ludolph, Albert C., Otto, Markus
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766627/ https://www.ncbi.nlm.nih.gov/pubmed/19890384 http://dx.doi.org/10.1371/journal.pone.0007638

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