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Specific Human Astrocyte Subtype Revealed by Affinity Purified GFAP(+1) Antibody; Unpurified Serum Cross-Reacts with Neurofilament-L in Alzheimer
The human GFAP splice variants GFAPΔ164 and GFAPΔexon6 both result in a GFAP protein isoform with a unique out-of-frame carboxy-terminus that can be detected by the GFAP(+1) antibody. We previously reported that GFAP(+1) was expressed in astrocytes and in degenerating neurons in Alzheimer's dis...
Autores principales: | Middeldorp, Jinte, van den Berge, Simone A., Aronica, Eleonora, Speijer, Dave, Hol, Elly M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766629/ https://www.ncbi.nlm.nih.gov/pubmed/19888461 http://dx.doi.org/10.1371/journal.pone.0007663 |
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