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Neonatal Injury Alters Adult Pain Sensitivity by Increasing Opioid Tone in the Periaqueductal Gray
Studies in both rodents and humans have shown that acute inflammatory pain experienced during the perinatal period produces long-term decreases in pain sensitivity (hypoalgesia) (Grunau et al., 1994a, 2001; Ren et al., 2004; LaPrairie and Murphy, 2007). To date, the mechanisms underlying these long-...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766783/ https://www.ncbi.nlm.nih.gov/pubmed/19862348 http://dx.doi.org/10.3389/neuro.08.031.2009 |