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Conditional Tek Promoter-Driven Deletion of Arginyltransferase in the Germ Line Causes Defects in Gametogenesis and Early Embryonic Lethality in Mice

Posttranslational protein arginylation mediated by Ate1 is essential for cardiovascular development, actin cytoskeleton functioning, and cell migration. Ate1 plays a role in the regulation of cytoskeleton and is essential for cardiovascular development and angiogenesis—capillary remodeling driven by...

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Detalles Bibliográficos
Autores principales: Leu, Nicolae Adrian, Kurosaka, Satoshi, Kashina, Anna
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767504/
https://www.ncbi.nlm.nih.gov/pubmed/19890395
http://dx.doi.org/10.1371/journal.pone.0007734