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Effects of Methotrexate on Plasma Cytokines and Cardiac Remodeling and Function in Postmyocarditis Rats

Excessive immune activation and inflammatory mediators may play a critical role in the pathogenesis of chronic heart failure. Methotrexate is a commonly used anti-inflammatory and immunosuppressive drug. In this study, we used a rat model of cardiac myosin-induced experimental autoimmune myocarditis...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhengang, Zhao, Pei, Li, Aihua, Lv, Xiaolei, Gao, Yang, Sun, Hongguang, Ding, Yongling, Liu, Jian
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768010/ https://www.ncbi.nlm.nih.gov/pubmed/19884981 http://dx.doi.org/10.1155/2009/389720

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