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Reductive Metabolism of AGE Precursors: A Metabolic Route for Preventing AGE Accumulation in Cardiovascular Tissue

OBJECTIVE: To examine the role of aldo-keto reductases (AKRs) in the cardiovascular metabolism of the precursors of advanced glycation end products (AGEs). RESEARCH DESIGN AND METHODS: Steady-state kinetic parameters of AKRs with AGE precursors were determined using recombinant proteins expressed in...

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Detalles Bibliográficos
Autores principales:	Baba, Shahid P., Barski, Oleg A., Ahmed, Yonis, O'Toole, Timothy E., Conklin, Daniel J., Bhatnagar, Aruni, Srivastava, Sanjay
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768164/ https://www.ncbi.nlm.nih.gov/pubmed/19651811 http://dx.doi.org/10.2337/db09-0375

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