Vascular Endothelial Growth Factor Inhibition by dRK6 Causes Endothelial Apoptosis, Fibrosis, and Inflammation in the Heart via the Akt/eNOS Axis in db/db Mice

OBJECTIVE: Vascular endothelial growth factor (VEGF), which is associated with the stimulation of angiogenesis and collateral vessel synthase, is one of the crucial factors involved in cardiac remodeling in type 2 diabetes. RESEARCH DESIGN AND METHODS: We investigated VEGF inhibition by dRK6 on the...

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Detalles Bibliográficos
Autores principales: Whee Park, Cheol, Wook Kim, Hyung, Hee Lim, Ji, Dong Yoo, Ki, Chung, Sungjin, Joon Shin, Seok, Wha Chung, Hyun, Ju Lee, Sang, Chae, Chi-Bom, Kim, Yong-Soo, Sik Chang, Yoon
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768173/
https://www.ncbi.nlm.nih.gov/pubmed/19675133
http://dx.doi.org/10.2337/db09-0136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768173/
https://www.ncbi.nlm.nih.gov/pubmed/19675133
http://dx.doi.org/10.2337/db09-0136

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