Cargando…
Vascular Endothelial Growth Factor Inhibition by dRK6 Causes Endothelial Apoptosis, Fibrosis, and Inflammation in the Heart via the Akt/eNOS Axis in db/db Mice
OBJECTIVE: Vascular endothelial growth factor (VEGF), which is associated with the stimulation of angiogenesis and collateral vessel synthase, is one of the crucial factors involved in cardiac remodeling in type 2 diabetes. RESEARCH DESIGN AND METHODS: We investigated VEGF inhibition by dRK6 on the...
Autores principales: | Whee Park, Cheol, Wook Kim, Hyung, Hee Lim, Ji, Dong Yoo, Ki, Chung, Sungjin, Joon Shin, Seok, Wha Chung, Hyun, Ju Lee, Sang, Chae, Chi-Bom, Kim, Yong-Soo, Sik Chang, Yoon |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768173/ https://www.ncbi.nlm.nih.gov/pubmed/19675133 http://dx.doi.org/10.2337/db09-0136 |
Ejemplares similares
-
Vascular Endothelial Growth Factor-Receptor 1 Inhibition Aggravates Diabetic Nephropathy through eNOS Signaling Pathway in db/db Mice
por: Yang, Keun Suk, et al.
Publicado: (2014) -
Acarbose Accelerates Wound Healing via Akt/eNOS Signaling in db/db Mice
por: Han, Xue, et al.
Publicado: (2017) -
Therapeutic Effects of Fenofibrate on Diabetic Peripheral Neuropathy by Improving Endothelial and Neural Survival in db/db Mice
por: Cho, Ye Rim, et al.
Publicado: (2014) -
Fenofibrate Improves Renal Lipotoxicity through Activation of AMPK-PGC-1α in db/db Mice
por: Hong, Yu Ah, et al.
Publicado: (2014) -
Cinacalcet-mediated activation of the CaMKKβ-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy
por: Lim, Ji Hee, et al.
Publicado: (2018)