Hypermetabolism, Hyperphagia, and Reduced Adiposity in Tankyrase-Deficient Mice

OBJECTIVE: Tankyrase (TNKS) is a Golgi-associated poly-ADP-ribose polymerase that is implicated in the regulation of GLUT4 trafficking in 3T3-L1 adipocytes. Its chromosomal locus 8p23.1 is linked to monogenic forms of diabetes in certain kindred. We hypothesize that TNKS is involved in energy homeos...

Descripción completa

Detalles Bibliográficos
Autores principales: Yeh, Tsung-Yin J., Beiswenger, Kristina K., Li, Pingping, Bolin, Krista E., Lee, Ray M., Tsao, Tsu-Shuen, Murphy, Anne N., Hevener, Andrea L., Chi, Nai-Wen
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768175/
https://www.ncbi.nlm.nih.gov/pubmed/19651815
http://dx.doi.org/10.2337/db08-1781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768175/
https://www.ncbi.nlm.nih.gov/pubmed/19651815
http://dx.doi.org/10.2337/db08-1781

Ejemplares similares