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Hypermetabolism, Hyperphagia, and Reduced Adiposity in Tankyrase-Deficient Mice

OBJECTIVE: Tankyrase (TNKS) is a Golgi-associated poly-ADP-ribose polymerase that is implicated in the regulation of GLUT4 trafficking in 3T3-L1 adipocytes. Its chromosomal locus 8p23.1 is linked to monogenic forms of diabetes in certain kindred. We hypothesize that TNKS is involved in energy homeos...

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Detalles Bibliográficos
Autores principales:	Yeh, Tsung-Yin J., Beiswenger, Kristina K., Li, Pingping, Bolin, Krista E., Lee, Ray M., Tsao, Tsu-Shuen, Murphy, Anne N., Hevener, Andrea L., Chi, Nai-Wen
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768175/ https://www.ncbi.nlm.nih.gov/pubmed/19651815 http://dx.doi.org/10.2337/db08-1781

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