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Nutrient Stress Activates Inflammation and Reduces Glucose Metabolism by Suppressing AMP-Activated Protein Kinase in the Heart

OBJECTIVE: Heart failure is a major cause of mortality in diabetes and may be causally associated with altered metabolism. Recent reports indicate a role of inflammation in peripheral insulin resistance, but the impact of inflammation on cardiac metabolism is unknown. We investigated the effects of...

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Detalles Bibliográficos
Autores principales: Ko, Hwi Jin, Zhang, Zhiyou, Jung, Dae Young, Jun, John Y., Ma, Zhexi, Jones, Kelly E., Chan, Sook Y., Kim, Jason K.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768176/
https://www.ncbi.nlm.nih.gov/pubmed/19690060
http://dx.doi.org/10.2337/db08-1361

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