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Genetic Variant in HK1 Is Associated With a Proanemic State and A1C but Not Other Glycemic Control–Related Traits
OBJECTIVE: A1C is widely considered the gold standard for monitoring effective blood glucose levels. Recently, a genome-wide association study reported an association between A1C and rs7072268 within HK1 (encoding hexokinase 1), which catalyzes the first step of glycolysis. HK1 deficiency in erythro...
Autores principales: | Bonnefond, Amélie, Vaxillaire, Martine, Labrune, Yann, Lecoeur, Cécile, Chèvre, Jean-Claude, Bouatia-Naji, Nabila, Cauchi, Stéphane, Balkau, Beverley, Marre, Michel, Tichet, Jean, Riveline, Jean-Pierre, Hadjadj, Samy, Gallois, Yves, Czernichow, Sébastien, Hercberg, Serge, Kaakinen, Marika, Wiesner, Susanne, Charpentier, Guillaume, Lévy-Marchal, Claire, Elliott, Paul, Jarvelin, Marjo-Riitta, Horber, Fritz, Dina, Christian, Pedersen, Oluf, Sladek, Robert, Meyre, David, Froguel, Philippe |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768183/ https://www.ncbi.nlm.nih.gov/pubmed/19651813 http://dx.doi.org/10.2337/db09-0652 |
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