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Direct cancer–stromal interaction increases fibroblast proliferation and enhances invasive properties of scirrhous-type gastric carcinoma cells

BACKGROUND: Scirrhous-type gastric carcinoma (SGC) exhibits an extensive submucosal fibrosis and extremely poor patient prognosis. We investigated the importance of the cancer–stromal interaction in the histogenesis of SGC. METHODS: Gastric fibroblasts NF-25 and intestinal fibroblasts NF-j2 were co-...

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Detalles Bibliográficos
Autores principales:	Semba, S, Kodama, Y, Ohnuma, K, Mizuuchi, E, Masuda, R, Yashiro, M, Hirakawa, K, Yokozaki, H
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768433/ https://www.ncbi.nlm.nih.gov/pubmed/19773759 http://dx.doi.org/10.1038/sj.bjc.6605309

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